Meta-analysis of chest compression-only versus conventional cardiopulmonary resuscitation by bystanders for adult with out-of-hospital cardiac arrest

Background: According to the guidelines of cardiopulmonary resuscitation (CPR) conducted by bystanders, two methods CPR are feasible: standard (sCPR) with mouth-to-mouth ventilations and continuous chest compression-only (CCC) without rescue breathing. The goal herein, was evaluate effect sCPR (30:2) CCC on outcomes in patients out-of-hospital cardiac arrest (OHCA) patients. Methods: This study a systematic review meta-analysis. Using standardized criteria, PubMed, Web Science, Scopus, EMBASE Cochrane Collaboration were searched for trials assessing vs. after adult OHCA. Random-effects model meta-analysis applied calculate mean deviation (MD), odds ratio (OR) 95% confidence interval (CI). Results: Overall, 3 randomized controlled 12 non-randomized met inclusion criteria. Survival hospital discharge ( SHD) 10.2% compared 9.3% group (OR = 1.04; CI: 0.93–1.16; p 0.46). SHD good neurological outcome measured cerebral performance category (CPC 1 or 2) 6.5% 5.8% 1.00; 0.84–1.20; 0.98). Prehospital return spontaneous circulation (ROSC) groups 15.9% 14.8%, respectively 1.13; 0.91–1.39; 0.26). admission ROSC occurred 29.5% 28.4% 1.20; 0.89–1.63; 0.24). Conclusions: concluded that there no significant differences between use compression only.